Tuesday, December 24, 2019

Critical Analysis Of The Sandy Hook Shooting - 1328 Words

On the morning of December 14, 2012, America experienced its deadliest mass shooting at a grade school and the fourth-deadliest mass shooting by a single person. All of America was left reeling as the details of what transpired were shared through every media outlet. Media reporters and American citizens were left wondering about how could this have happened and how could we have prevented this heinous crime. In looking for an explanation the Media emphasized various topics such as mental health, violent video games, and gun control as possible catalysts. This essay will provide a critical analysis of what happened in the Sandy Hook Shooting, the media’s role in public opinion, and the arguments laid forth by claims-makers as associated†¦show more content†¦In the classroom teacher, teacher’s aide, and all 14 students are killed. Moving on to a second classroom, Lanza killed another teacher, teacher’s aide, and 6 students. It is in this second classroom where Lanza commits suicide. Within minutes 26 people were killed, 20 of them being children between the ages of 6 and 7 years old. The weapon used by Adam Lanza during the shooting was a Bushmaster .223-caliber rifle. Found near his body were a semiautomatic .223-caliber rifle and two handguns. In the car, there was an Izhmash Saiga-12 (CNN Library 1). All the guns were legally purchased and registered by his mother, Nancy Lanza. Investigators would soon find out that Nancy was an avid gun collector and enthusiast. Not only did Nancy provide access to the weapons, she also brought Adam and his older brother to a shooting range for target practice (Bankcoff 1). Adam Lanza, 20 years old at the time of the shooting, had been diagnosed with Asperger’s syndrome and Obsessive-Compulsive Disorder. According to a report by Connecticut’s Office of Child Advocate Lanza was an individual with deteriorating mental health and a fascination with mass shootings. Before the shooting, Lanza had cut off all communication to reality, secluding himself to his room where he played hours of violent video games and obsessed over mass murders. During the police investigation, his computer was found to contain stories, movies, and video games all related toShow MoreRelatedCritical Analysis Of The Sandy Hook School Shooting1520 Words   |  7 PagesOn the morning of December 14, 2012, a lone shooter entered Sandy Hook elementary school and killed 26 people. This heinous crime is America’s deadliest mass shooting at a grade school and the fourth-deadliest mass shooting by a single person. Throughout the country, American citizens were mournful and regretful as media outlets released the details of what transpired. Police investigators, media reporters, and American citizens were left wondering how could this have happened and how could we haveRead MoreEffects of Violent Media on the Youth Essay1700 Words   |  7 Pagestrilogy which includes violent depictions of beatings, graphic shootings, dozens of explosions, neck snapping and back breaking, along with chokings, hand to hand combats, and dead bodies. These portrayals are detailed, but little blood is shown. While violence is not a new thing to the world, it is a problem that is skyrocketing in correlation to modern society and violent movies, video games, and media. With school shootings like Sandy Hook, Virginia Tech, and Columbine, many psychologists have askedRead MoreDesigning Curriculum, Instruction, And Assessment1125 Words   |  5 PagesSpecialist, my role is to coach teachers and assist them with technology integration. I will call upon the International So ciety for Technology in Education (ISTE) standards for students, Standard 3: Research and Information Fluency. This standards is critical for our grade six students to master as they will experience their first major research project as per the curriculum, but it’s also a concept that they must use in the future whether it be for classwork, their personal lives or career. RecentlyRead MoreGun Control : Is It The Answer?1346 Words   |  6 PagesChase Brosie Professor Anderson ENGL 1302 13 November 2015 Gun Control: Is it the Answer? â€Å"After a shooting spree, they always want to take the guns away from the people who didn t do it. I sure as hell wouldn t want to live in a society where the only people allowed guns are the police and the military.† William S. Burroughs In recent history, one touchy subject that has been argued over quite often is whether or not we should crack down our gun laws. This issue has come to the forefront of everyone’sRead MoreWorkplace Violence1735 Words   |  7 Pagesand claims of workplace violence, with 458 being homicides1. Workplace violence is at the forefront of everyone’s mind when a breaking news story is broadcast on the evening news, such as the recent shootings in Santa Cruz, California by a disgruntled ex-cop, and the Sandy Hook Elementary School shooting in Newtown, Connecticut, but workplace violence can strike anywhere and at any time, and is a major concern for employers and employees across America. There are different types of workplace violenceRead MoreBronfenbrenner s Theory And Conduct A Case Study Analysis2426 Words   |  10 PagesIntroduction The purpose of this paper is to apply Bronfenbrenner’s theory and conduct a case study analysis about a terrifying massive shooting involving Adam Lanza who had acted out destructively against society bringing terrors to the families in Newtown, Connecticut. It is difficult to choose one developmental theory that is a perfect fit to any one person’s development being that each theorist has very relevant and valid ideas about human development. Bronfenbrenner proposes that each individual’sRead MoreThe Effects Of Violent Video Games On Children Essay1670 Words   |  7 Pagesexposed to these types of games, their children might perform the acts of what they are playing. Parents are understandably worried for their children playing these violent video games and the fact that there have been many school shooting in recent years such as Sandy Hook, Columbine, Virginia Tech are just examples of a few egregious acts that have resulted in countless deaths of teenagers . It has been observed that playing violent video games, watching sadistic movies and media that include deathRead MoreThe Impact Of Social Media On The Criminal Justice System1920 Words   |  8 Pagespowerful tool utilized to broaden intelligence gathering as well as leverage public support in critical and detrimental circumstances, all of which impact the criminal justice system. Although positive on many fronts, the effects of social media can be damaging to our society. Social media has the potential to change the dynamic of society. With regards to the criminal justice system, this analysis will evaluate the ways in which social media has aided as well as impeded the criminal justice systemRead MoreActive Shooter7891 Words   |  32 Pagesthing parents expect is something terrible happening to their child while at school. School violence is happening more frequently than it should and something needs to be done to stop it. Not only does an act of school violence, especial ly a school shooting, affect the individual student it reflects poorly on the United States school systems but it also reflects poorly to our nation as whole. Some people may argue that there is more pressure on kids these days than ever before and this can lead childrenRead MoreMental Health Awareness And Improvement Act Of 20132897 Words   |  12 Pagescan productively integrate practical insights reached from a variety of different points of view. Part A: Legislation and Political Context Senate (S.) 689 is the Mental Health Awareness and Improvement Act of 2013, which resanctions and increases critical behavioral health programs through superior federal education and healthcare programs related to awareness, early identification, and prevention of mental illness (The Library of Congress, 2013). United States Senators Tom Harkin (D-IA) and Lamar

Sunday, December 15, 2019

Virtual Organization Employment Law Free Essays

Globalization and the development of the Internet technology have brought serious changes in our world today. It is as if the other side of the world is just a few seconds away. Countries which previously closed their borders to the international community were forced to open up. We will write a custom essay sample on Virtual Organization Employment Law or any similar topic only for you Order Now People who were previously isolated from the rest of the world are now being brought together by the necessity for survival in this competitive world. The desire for strong trading relations with other countries forced countries to build political alliances with other countries. Corporations need to continuously grow to meet the ever-changing needs of the consumers. Riordan Manufacturing Inc is no exception. Riordan Manufacturing, Inc is currently the leader in the field of plastic injection molding. Its mission is to provide innovative solutions, products and services at a reasonable cost and to develop long-term relationships with its customers. To meet the demands of its world-wide clientele it opened its facilities in San Jose, California, Albany, Georgia, Pontiac, Michigan and Hangzhou, China. These changes, however, which were brought about by globalization also created complexities on the part of the employers insofar as employee management is concerned. The differences in cultural identities and the unique practices of employees are bound to create employee-related problems for the company. With the congregation of different people, each having his own identity, in one single company, tension and conflicts were likewise created. (Diana Ayton-Shankar) Discrimination and sexual harassment issues are also bound to arise which the company is bound to anticipate. Research shows that in a study conducted by the National Organization for Woman, they found that 80% of women surveyed in a wide variety of industries had been sexually harassed. The EEOC now handles some 5,000 new sexual harassment cases annually, double the caseload of only a few years ago. (David J. Bowman) If these concerns will not be addressed by the company, then the company may expose itself to suits. There was a case in San Francisco wherein the jury awarded the amount of more than $7M to a legal secretary harassed by a male partner in a law firm for failing to act swiftly on a sexual harassment complaint. Gerald D. Bloch) Thus, creating a non hostile and friendly working environment should also be one of the top priorities of Riordan Manufacturing, Inc. Discrimination Issues in the Workplace Since the business organization is composed of personnel coming from different countries, there is a possibility that the company may have in its employ Americans and Asians. The possib ility, therefore, of racial discrimination and sexual harassment issues among the employees is not remote. In a multi-racial organization, racial discrimination is a pressing issue which must be properly be addressed by the management. Some Managers, consciously or unconsciously prefer white employees over the black employees or Asians, considering that Riordan has facilities in China. In some business organization, the white Americans are given better work opportunities than Black Americans or Asians. In some organizations, most black employees are being hired for rank-and-file positions or they are disqualified for promotion on the simple basis of their color or race. Another issue that the Riordan Manufacturing Inc may encounter is gender discrimination. Although the labor laws expressly prohibit gender discrimination in the workplace, it is still being practiced in several business organizations. For example if Riordan Manufacturing, Inc prefers to hire male applicants over a female applicant though they are similarly qualified for the position, it will be an outright discrimination on the ground of gender discrimination. As mentioned, there is always the possibility that sexual harassment may occur in Riordan Manufacturing Inc. Sexual Harassment is defined by the EEOC as any unwelcome sexual advances, requests for sexual favors, and other verbal or physical conduct of a sexual nature when: a) submission to the conduct is made either explicitly or implicitly as condition of an individual’s employment, or b) submission to or rejection of the conduct by an individual is used as a basis for employment decisions affecting such individual, or c) the conduct has the purpose or effect of unreasonably interfering with an individual’s work performance or creating an intimidating, hostile, or offensive working environment. â€Å"Preventing Sexual Harassment: A Fact Sheet For Employees†) State and Federal Statutes on the matter of discrimination are clear. Job treatment which includes the hiring of employees, firing of employees, and promotions of employees, must be based on qualifications and merit and not on race, gender, age, sexual preference, disability. (â€Å"Workplace Harassment and Employ ment Discrimination†) In these cases, it is not only the legal duty of every Human Resource Manager but its ethical duty as well to incorporate in its policy manual the rules against discrimination. They must include in their policy manual that the management does not tolerate any form of discrimination in the business organization. It must define the acts that constitute discrimination. The policy manual must likewise include the procedure for filing of complaint against the person who utters discriminatory remarks or practices discrimination in the workplace and the penalty for those who will be found guilty after investigation is conducted. Indeed, communication is a key to avoiding discrimination in the workplace. There must be communication by the employer in the sense that they must inform their employees that discrimination will not be tolerated by the company and that any incident of discrimination will be seriously dealt with. There must also be communication between the offended party in the sense that both parties must be given by the management opportunity to meet so that the offending party may know that the act or remark given is offensive and discriminatory. It is possible that the other person does not have any knowledge or idea that the remark he has just uttered or the act he has just committed is offensive to the sensibilities of another. If despite the fact that he has confronted and communicated his feelings to the other person he still continues making discriminatory acts and remarks, the victim of discrimination must seek assistance from his supervisors. If there is no company policy against discriminatory acts, the victim of discrimination must report and notify immediately his immediate superior, the supervisor or the Human Resource Manager so that this could be acted upon. To strongly implement the policy against discrimination sanctions against those who have proven to commit such acts must be put in place. Among the sanctions that could be imposed are written warning, letter of reprimand, suspension, change of job or class assignment and termination or expulsion. Conclusion I have identified three major discrimination issues that is likely to happen in Riordan Manufacturing, Inc. and explained the manner by which the company may address these issues. Indeed, discrimination issues in the workplace should not be treated as something which ordinarily happens in the workplace. It can be avoided. A friendly, nondiscriminatory, and non-hostile environment is not a utopia. The task therefore of Managers is to anticipate these problems or if it already exists in the workplace the Managers must find solutions to these problems. Indeed, the failure to resolve these issues may lead to serious losses to the employer as it affects the performance of the employee involved. How to cite Virtual Organization Employment Law, Papers

Saturday, December 7, 2019

Reflection on Placement Experience for Health Care - myassignmenthelp

Question: Discuss about theReflection on Placement Experience for Health Care. Answer: Introduction: Health care is undoubtedly one of the noblest professions, and that is the reason, thousands of aspirants chose health care as their choice or career every year and enroll themselves onto different healthcare courses. However, healthcare is a people centered profession influenced by a variety of different external and internal factors, and hence the health care professionals often face a number of key challenges when they have to apply their theoretical knowledge in the practical scenarios. The placement program is the wonderful opportunity for the health care professionals to get a clear idea of all the variables of a real world health care scenario and attempt to link their own theoretical knowledge to application building expertise in their chosen domain (Levett-Jones, Pitt, Courtney-Pratt, Harbrow Rossiter, 2015). This assignment will attempt to reflect upon the placement experience I have received and how it had helped me in my professional growth. I had been given the opportunity to attend the placement program in the esteemed calvary health care Bethlehem in Caulfield. This health care facility had been provided an exceptional and commendable quality of care since the year of 1885. It is a nonprofit catholic health care organization established by the Sisters of the Little Company of Mary. This health care organization caters to the Victorian community with supporting more than 4000 patients and their families every year; with the mission of providing compassionate and quality care to the patients at all stages of their lives. This pioneer health care facility specializes in two areas, progressive neurological diseases and specialist palliative care services (Services at Calvary Health Care Bethlehem., 2017). I had been given the opportunity to experience the health care environment of the palliative unit of the health care organization during my placement program. This division of the health care facility is focused on the patients who have a progressive incurable disease, and provides both residential and at home support to these patients that are in the end of life stage of life. The main goal of the palliative unit of the health care facility is to provide an optimal end of life acre to the patients so that they can achieve dignity, comfort and sense of safety during his or her stay in the facility (Palliative Care - Calvary Health Care Bethlehem., 2017). Considering the patient population of this division of the health care facility, close to 40% of the total patient population receives end of life care in the palliative units of the health care facility. The staffing ratio if the patient population of the palliative unit is 5:1, where on nursing professional has the responsibility o f 5 terminally ill patients (Calvarycare.org.au., 2017). The initiatives taken by the palliative unit for achieving the ultimate goal of maximizing the quality and patient centeredness of the care include devising and supportive GP and primary care team, community palliative day care centre, management of distress symptom, providing necessary equipment and home based care in critical situations, proper patient and family education, and 24*7 telephonic assistance (About Us - Calvary Health Care., 2017). A critical incident analysis evaluates and analyzes the a particular critical incident occurring in a health care scenario, reflecting upon the professional, moral and legal issues that arise in the scenario. The critical incident that I encountered in the placement program had been involving a 65 year old patent named Jessica day with unresectable chondrosarcoma in the left thigh that had started to infiltrate the outer muscles. The patent had been referred to the palliative unit right away to plan for an end of life care plan for the patient. However within a few weeks of her stay, a critical incident occurred where the patient developed paresthesia and acute pain in the backside of the infected thigh and leg. The pain score as assessed by Abby scale of pain management had been 8 out of 10. Now, the critical incident had been handled in accordance with the WHO guidelines of cancer pain management. She had been prescribed oral dose of morphine 10 mg quarterly, and along with a conco ction of 400 mg ibuprofen and 500 mg paracetamol had been prescribed in a quarterly manner as well. However, the patient was only relieved from the pain for a few hours, after which the pain returned again; however along with that the patient started feeling increasing numbness in the leg and she started experiencing anxiety and insomnia. It has to be understood that the patient had advanced cancer and had been undergoing neuropathic pain and the care facility had the lack of correct mechanism to manage neuropathic pain. This sincere professional issue had been prevalent in the case study, although as the care facility did not have a specialized advanced oncology department, and the patient had not been in a condition to be moved the patient, the only intervention technique possible had been utilized. The patient had wanted to be removed from the ICU unit and off the analgesic treatments, however despite the legal mandates of patient centered care; this particular wish of the patient could not be fulfilled due to the fast deteriorating condition of the patients. However, the care pan had been decided on with accordance to the personal preferences of the family members of the patient. However the patient had been given the opportunity to spend her last few days with her family in the palliative unit, so that morally the best experience could be given to her. Conclusion: On a concluding note, it can be stated that the palliative unit of the calvary health care facility had been an exceptionally compassionate care service and they prioritize the welfare of the terminally ill patients above everything. Although in my placement experience, the critical incident I encountered could have been better managed if specialized oncology care training to the staff had been given in the facility. I have gotten the opportunity to understand the complexities that can arise while working in the palliative units, and will work towards professional growth that will enable me to handle such situations much more efficiently. References: About Us - Calvary Health Care. (2017).Calvary Health Care. Retrieved 7 November 2017, from https://www.calvarycare.org.au/about Palliative Care - Calvary Health Care Bethlehem. (2017).Calvary Health Care Bethlehem. Retrieved 7 November 2017, from https://www.calvarycare.org.au/public-hospital-bethlehem/services-and-clinics/palliative-care/ Services at Calvary Health Care Bethlehem. (2017).Calvary Health Care Bethlehem. Retrieved 7 November 2017, from https://www.calvarycare.org.au/public-hospital-bethlehem/services-and-clinics/ Levett-Jones, T., Pitt, V., Courtney-Pratt, H., Harbrow, G., Rossiter, R. (2015). What are the primary concerns of nursing students as they prepare for and contemplate their first clinical placement experience?.Nurse Education in Practice,15(4), 304-309. Doi: https://doi.org/10.1016/j.nepr.2015.03.012 Calvarycare.org.au. Retrieved 7 November 2017, from https://www.calvarycare.org.au/public-hospital-bethlehem/wp-content/uploads/sites/5/2016/05/Calvary-Bethlehem-Palliative-Brochure-6pp-DL_2016.pdf

Saturday, November 30, 2019

The Need For Honesty Essays - Virtue, Chinese Philosophy

The Need For Honesty The Need for People Honesty. Everyones heard the tale of the Boy who cried Wolf right? Sure, shepherd boy thinks he's funny, makes a fuss about imaginary wolfs, villagers come running - no wolf. Then when wolfs actually do come, he yells and screams, yet villagers weren't about to play his game again, his sheep get nailed by the wolves. Moral of the story. Liars are not believed even when they tell the truth The reasons people are less than truthful are many, they do it because they lack the courage to say what they think, they do it because they are comfortable in their pretensions, and they do it because they are insecure. I spent a long time asking myself why should people be straight up, what moral chains are there? It's to easy to say because society expects it, or because history has presented its heroes as paragons of virtue. No, I believe the reason to be much more selfish, the need for people to be straight-up is that individually you become better people for it. But why? Why would you be a better person for speaking the truth? If you leave behind all the morality, all the chains of ethics, all the issues of virtue. What is it? If truth was an object or feeling how would you describe it? Is it a goal to strive for? A gut feeling? An instinct to pass on your interpretation of events without deviation? Who knows exactly? All I know is that I hold it high, and I refuse to abnegate this belief for anyone, better yet I expect people to follow suit. Never am I more disconcerted than if someone I trust has lied to me, to my face, how dare they? Why do we feel this way? because we just do?...Neh.. To easy, because society demands that we do? No, I don't feel bad if someones lied to me because society says they shouldn't. No, I feel bad because I've been betrayed. I trusted them to be like me and they weren't. I trusted them to hold the same set of beliefs that I do, and they didn't. Yet the only way I can expect that of them is if I have a sure fire justification that my way is right...but I don't so where am I? Who knows? Is honesty some common unspoken societal belief? Or spawned of some religious base? Or are people only honest because they fear retribution? Are they better people for speaking it out of fear, and not obligation? These questions have been asked for centuries, the dude who told The Boy Who Cried Wolf was born in the 6thCentury Before Christ. He was a slave to Egyptian King Cleombrotus, his name was Aesop. The questions have been answered using words like nobility, integrity, and virtue. Yet none of them fit, none of them completely explain why people owe it to each other to be honest. This is because they don't owe anything to each other, they owe it to themselves. People that lie go against the grain, they are frowned upon and rightly so. Deep inside everyone knows that if they lie its wrong, a little fib here, embellishment there, whats the harm? I'll tell you what the harm is, its a *censored* load of grey in my life that I don't really need. Philosophy Essays

Tuesday, November 26, 2019

buy custom Benefits of Information Technology essay

buy custom Benefits of Information Technology essay Cost Savings and Revenue-Enhancement Factors that Are Realized with New Technology Automated Processes and the Ability to Work Remotely With the implementation of new Information Technology (IT) systems comes improvement in productivity, high degrees of accuracy in the information circulating within firms and better profit performance of firms. IT helps the business to process large volumes of data and information at a relatively shorter time. It therefore, follows that the beneficiaries of such information such as the employees and the management have access to reliable and accurate data and information which is critical in surviving in todays highly dynamic and competitive business environment. Saving time in carrying out business functions and processes also helps firms to cut overhead costs of carrying out lengthy and redundant business processes (Sheahan, 2011). For example, in the past, some companies have had to seek services of other firms in computing their incomes and expenditures at the end of each fiscal. Today, these business functions have been made even simpler and cheaper since firms only maintain lea n departments tasked with other jobs as computations can easily be analyzed by use of spreadsheets and other relevant software. Therefore, while the companys employees are involved in other tasks, due to autoation of computers, it can also automatically run its reports, monitor business financials, create custom system queries, and track project progress. Ease and Cost of Communication The availability of both local and international networks has improved the performances of businesses communication and cut down on travel costs because businesses can share large amounts of voice data and video services across their businesses. With outsourcing and other business operations aimed at maximizing profits and minimizing operational costs, IT systems have come in handy in effecting communication where numerous businesses and organizations are controlled by one head office (Stair Reynolds, 2011).For example, even while on a long business trip, the secretary can still furnish the business president with information and by use of the companys electronic network, the president can access the companys data bases and information. This ensures continuity of business processes even when management is not physically available to supervise operations. Electronic Storage and Protection of Records IT systems enable electronic storage functions that are capable of storing massive volumes of important business records in form of raw data and information. Secure and confidential storage of client data and informatioon is critical in gaining the integrity and confidence of business associates and clients. Storage facilities for example, storage vaults securely keep data by allowing only authorized personnel to access that information. Changes or lose of information and data are minimized or even eliminated as they are only available to authorized users with due rights and privileges. The security and cost of maintaining crucial data are realized because office space is saved and security enhanced due to the security protocols employed to secure information and data in the companys data bases. Section 2 Importance of the these Factors All the above benefits that come with the IT systems in an organization are geared towards the achievement of efficiency and maximization of productivity in a firm, secure storage, and ease of access of business information and cheap and fast communication. When a business organization achieves these important elements, the costs of doing business are significantly minimized (Sheahan, 2011). Also, due to efficiency attained by saving of both time and finances of an organization, the incomes of a firm are optimized. A firm that has sound understanding of IT applications easily gains a competitive edge especially in todays IT-driven world thus remaining ahead of competition. Buy custom Benefits of Information Technology essay

Friday, November 22, 2019

Application Of Nano Medicine In Various Fields Of Medicine

There isnt generally any area of medicine which couldnt benefit by the upsides of nano technology. The usage of nano materials enable imaging with an upgraded three-dimensional view by strategies for which particular sorts of tissue can be isolated more viably and the measure of distinction medium required can be reduced essentially. Characteristics, nucleic acids, proteins, particles and cell strategies can be distinctively changed electronically and optically with the guide of quantum spots, i.e. nanoparticles of semiconductor valuable stones. These photo probes convey brilliance 1,000 times more imperative than that of customary many-sided quality media and can be contrastingly balanced electronically and optically in light of their colossal security and brightness. The desires and wants for the characteristic potential results of nano medicine pivot around early distinguishing proof of ailments and inherited mentalities at the nuclear level with the guide of fundamental and effic ient quick tests and correct imaging techniques. Researchers are tackling instruments which are advantageous and decentralized and which require only the humblest measures of test for conclusion. The to an awesome degree downsized lab-on-a-chip technique fundamental for this is correct, efficient and of little weight to the patient. It can be used as a piece of the experts preparation and specialists offices and for keeping the spread of powerful diseases. Scientists are hopeful that nanotechnology applications will progress existing and develop new pharmaceuticals and systems for checking, controlling and assuaging diseases. Falsely made vaccinations against powerful illnesses and invulnerable framework contaminations, solutions can be taken by essentially taking in and more profitable possible pharmaceuticals of cardiovascular infections will be available. Creative work is going on centered transport of dynamic substances, affirmation of which is in every way possible now with the guide of nanotechnology. Biocompatible, round nano materials (for example polymers, liposomes or micelles) can be used as transporting administrators. Such vehicles in the unfilled inner parts of which dynamic substances can be transported and the surfaces of which can be furnished with sensors which perceive compound states or cell composes, diseases and distinctive pathogens add themselves to these and can release the dynamic substances to the target with out the including tissue being hurt. Nano medicine for early diagnosis of cancer One of the essential cause of deaths worldwide is cancer which accounts to 7.6 million persons (around 13 % everything being equivalent) in 2008.Countries of Western World and in the US are standing up to progressively the extended risk of development, which ought to be the second driving explanation behind death after heart-attack. There will be 15 million new occasions of tumor worldwide in 2020 as demonstrated by the World Health Organization (WHO). Most of the tumor related deaths occur by the spread of debilitating danger cells to major organs by a method called metastasis. Pharmaceutical and biotechnology associations are impacting package of research intrigues remembering the true objective to accommodate specific prescriptions that can pound fundamental and discretionary tumors, i.e. which result from metastasis to various organs. Nano technology in cancer treatment is currently a reality giving a huge variety of new instruments and potential results, from earlier restorative distinguishing strength and improved imaging to common, more capable, and more centered around medications. Development biomarkers are markers made by tumor cells spreading in the body and are typically used for malady acknowledgment which are at any rate introduce in too low obsessions to be successfully recognized in beginning times. Coordinated transport of specific nanoparticles into these tumor cells can start an area correspondence with illness cells which urges them to inside and out grow the production of these biomarkers. In like manner area ends up being therefore significantly less complex with biomarkers and can give an earlier investigation to authorities than biopsies. Ideal area of tumor allows brisk and less troublesome medicines moreover extending the chances of recovery. Appealing properties of iron oxide nanoparticles attach amazingly well to the tumors and make them appropriate imaging authorities with MRI-checks whereas their size and obsession in the tumor enable a high assurance and an exact mapping of wounds. Authorities would in this way have the capacity to rely upon thusly to pick and pick the cautious clearing of the tumor. Treating threat by show chemotherapy medicines or characteristics allows considerably more confined movement diminishing basically the measure of solutions devoured by the patient for ascend to influence and the responses on the incorporating strong tissues in the body. By nano medicine system nanoparticles can be implanted into the tumor and after that be established to make warm and pulverize danger cells either by appealing fields, X-pillars or light. Nano medicine for fighting diabetes Notwithstanding the way that diabetes is never again considered as a risky illness after the disclosure of insulin treatment it is up till now considered the fifth most typical explanation behind death in the U K. likewise diabetes is a disorder which significantly impacts patients close to home fulfillment and can even provoke genuine helper afflictions for instance visual debilitation and neuropathies. Nowadays two examples related to diabetes are conspicuous: An electrifying addition in the amount of patients with type 2 diabetes mellitus t2dm a lifestyle and chubbiness related brokenness of glucose control The disease is as of now happening in earlier ages generally in the midst of pre-adulthood or from time to time in the midst of youthfulness while in the past it affected primarily the old people. Immature diabetes or type 1 diabetes t1dm is caused in light of the insusceptible framework induced complete decimation of insulin-conveying beta-cells in the exocrine organ. The drugs available at present require dependable imbuements of exogenous insulin a couple of times every day. Notwithstanding what may be normal starting time of t2dm can be managed by changes in eat less carbs by physical exercise and by drugs putting off the glucose take-up in blood. The different imbuements of insulin in late t2dm after weariness/pummeling of the beta cells and in t1dm impact patients close to home fulfillment since it is long meddlesome horrifying and along these lines basically striving for the youngsters. What’s more it doesn’t allow complete control over the glucose level which in the most negative situation can provoke neurologic or vascular issue. For a drawn-out period of time the principal look into in the fight against diabetes has in light of the progress of upgraded non-meddling watching and hormone association and furthermore the transplantation of islets in pancreas without invulnerable covering in t1dm-affected children. The use of nanotechnologies to decide therapeutic issues can give promising advances to help the individual fulfillment of diabetes patients. Acting at the nano scale with structures that are generally 10-100 times tinier than a body’s cell yet hardly greater than particles makes possible the treatment of this polygenic sickness at the sub-nuclear level. For instance ponder on the transport of hypoglycemic pro as nanoparticles inside the nose or into the lungs as a sprinkle or through the gastrointestinal tract as a pill are at the same time. In both the cases non-prominent and easy application courses are opened by crafted by nanoparticles. Furthermore tests are correct presently being driven o n nano materials worked with a glucose responsive covering which may go about as an insulin storeroom once mixed under the skin. Nano-based imaginative sensor systems are in like manner under research with the purpose of upgrading non-prominent or less meddlesome seeing of glucose level in the blood. As for a more present approach is a glucose-fragile tattoo. Likewise new safe protective nano-coatings can postpone the survival of transplanted pancreatic channels and guarantee them against the autoantibodies in t1dm patients. This approach concentrating on t1dm patients would enable them to experience a presence without safe suppressive drug. The desperation of continuous systems to fight this polygenic issue which transforms into a pandemic ailment and end up to an imperative shorter future 10 years in t2dm >20 years for t1dm and to high expenses for prosperity structures is unquestionable. Novel systems using moved nanotechnologies can deal with this test and will therefore be one of the key research subjects in the forthcoming EU framework program.

Wednesday, November 20, 2019

Street art in Berlin Essay Example | Topics and Well Written Essays - 1250 words

Street art in Berlin - Essay Example At the time, graffiti artists among other citizens took to the wall on both sides using the wall to criticize the erection of the wall with every artist striving to communicate specific messages. Such messages as â€Å"Death to tyrants†, â€Å"God Ble$$† and â€Å"Concrete makes you happy,† conveyed the opinions of the people regarding the separation of Germany into two. While street arts were illegal at the time, the graffiti artists among others enhanced the artistic criticism of the society at the time thereby contributing to the demolition of the wall. Germans did not like the wall since it split their country simply to serve political interests. West Germans used their side of the wall to express their disgust with the wall and so did the Eastern Germans. Streets arts, as exhibited on the Berlin wall, became an integral culture in Germany. In the 1970s, streets artists sought to make Berlin their Mecca. They devised new mechanisms of developing systematic gr affiti with paint cans being among the most favorable. Key among the targeted platform for the streets artists were the communist property (Schürer 101). The defaced such property in a defiant attitude. The artists expressed their displeasure with the prevailing political developments while expressing their desired developments. The areas around the wall of Berlin consisted of dilapidated streets, abandoned buildings and piles of rubles, which the street artists took over splashing defiantly yet creative criticism of the society.

Tuesday, November 19, 2019

Critically discuss the positive and negative effects which 'The Essay

Critically discuss the positive and negative effects which 'The Private Life of Henry VIII had upon the British film industry of - Essay Example Quotas and Quickies in British Film Industry Hollywood has begun to overrule all other filming industries around the world, making the competition of international and local cinemas rise. In England, 1930’s â€Å"were turbulent years† for the British filming industry, as the import of Hollywood films became more popular than the locally produced films (Aldred, 1996.). As an action from the government, a legislation was passed ordering all movie houses to showcase British products. Although it was a good act to make, the unexpected result happened as the mediocre, low-budget British films were made so as to fulfill the legislation and avoid any legal impediments. The Cinematograph Film Act of 1927, instead of successfully addressing the problems of British movie’s audience share, produced a line of â€Å"quota quickies† or movies made for the sake of following the legislation. In other words, a large number of British movies of that time period were based o n quantity, not quality and consequently failed to reach the minimum profit of each movie shown. This Act of Parliament, although considered a failure, brought British film making into a more active state compared to the period before the law was enacted (Richards, 2001, p. 57). The Film Act of 1927 became known throughout Europe, and some countries like Germany did the same legislation in order to enhance their own locally-produced films (Richards, 2001, p. 59). Quota quickies were born out of the legislation from the Parliament to enhance the production of British films, and not to bombard the cinemas with mediocre outputs. Realizing the inability and less use of the Cinematograph Films Act of 1927 to the proliferation of quality British films, another Act of Parliament was made to amend the flaws of the previous legislation. Cinematograph Films Act of 1938 ordered the raise of British film quotas from 5 per cent to 15 per cent and required all British films to be worthy of passin g the international standards, thus, debunking the typical perception of the British movies in the 1930’s. Following the decline of the U.S. market on the period of the Great Depression, local movie producers were given the â€Å"space [to create] new and unusual films† (Ashby & Higson, 2000, p. 57). This also served as the first manifestation of the American presence in the British-made films. Metro Goldwyn Mayer (MGM), an American film production company was the first one to make British-inspired films, which were huge successes for both British and American audience. Consequently, America’s great depression forced American producers to seek refuge in the British lands. British setting is not unusual for the American audience, with the British history as mandatory subject in schools. According to Reynolds (n.d.), the appreciation of British-set movies by American movie goers stems from the interest of the Americans of â€Å"British traditions and institutions especially of the class system† (cited in Ashby & Higson, 2000, p. 58). Ashby and Higson’s (2000) claim about the class system as marketable topics in

Saturday, November 16, 2019

Training in Diversity Essay Example for Free

Training in Diversity Essay Skills and expertise in a specific type of job is necessary in order for a person to be selected in positions in certain companies. Nowadays, having the financial and economic crisis, companies tend to choose personnel with the highest or best expertise from the pool of apprentices in the desired field of work. It will be a waste of time and money if the companies will no t be able to get a quality and efficient personnel. In observing the business world, the recession has not greatly affected the food industries except for the breakout of melamine and Salmonella for some cases, and I can say telecommunication services still have its place unmoved. I observed that companies with the aim of hiring and getting professionals in the job or places of the representatives are conducting trainings that might bring out their potentials offer degrees, say a 6 month review and hands on training with the supervisors and other professionals. Since the job needs skilled people, the requirement to become a certified customer care representative is at least a Bachelors Degree and a proficiency in English. Bishop and Company in Waipahu Hawaii, for instance opens a number of position for customer care representatives but provides a temporary contract with the workers, thus only have 8 hours work at day time. On the other hand, in the Philippines, particularly BPO Training Academy caters a number of trainings that will aid the call center agents or representatives to deal with the problems and the sole nature of the work. The company provides an outlook of a job thus giving its student quality education that in turn is a tool in overcoming the struts and frustrations of a call center agent. Moreover, even if the company requires fees for the training, the students have assurance for employment for the company has a number of partners that are in line with providing best service and assistance on line. References Customer Care Representatives. Occupational Outlook Handbook, 2008 – 09 Edition. Retrieved 26 February 2009 from http://www. bls. gov/oco/ocos280. htm#training

Thursday, November 14, 2019

The Central Question of Hamlet Essay -- Essays on Shakespeare Hamlet

The Central Question of Hamlet  Ã‚      Hamlet's tragedy is a tragedy of failure-the failure of a man placed in critical circumstances to deal successfully with those circumstances. In some ways, Hamlet reminds us of Brutus in Shakespeare's "Julius Caesar." Hamlet and Brutus are both good men who live in trying times; both are intellectual, even philosophical; both men want to do the right thing; both men intellectualize over what the right thing is; neither man yields to passion. But here the comparison ends, for though both Brutus and Hamlet reflect at length over the need to act, Brutus is able immediately to act while Hamlet is not. Hamlet is stuck "thinking too precisely on th' event-". Hamlet's father, the king of Denmark, has died suddenly. The dead king's brother,Claudius, marries Hamlet's mother and swiftly assumes the throne, a throne that Hamlet fully expected would be his upon the death of his father. Hamlet's father's ghost confronts Hamlet and tells him that his death was not natural, as reported, but instead was murder. Hamlet swears revenge. But rather than swoop instantly to that revenge, Hamlet pretends to be insane in order to mask an investigation of the accusation brought by his father's ghost. Why Hamlet puts on this "antic disposition" and delays in killing Claudius is the central question of the play. But Hamlet did not swear to his dead father that he, detective-like, would investigate. Hamlet swore revenge. And he has more than enough motivation to exact revenge. Does it not, think thee, stand me now upon- He that hath killed my king, and whored my mother; Popped in between th' election and my hopes, Thrown out his angle for my proper life, And with such cozenage-is't not perfect cons... ...play that is flawed, not our understanding of it. The central question of the play is, then, a question without an answer if one is seeking the answer within the play. Shakespeare was supposed to supply us with an answer, or at least with a reason why there is no answer. He offers us neither. Instead, this most celebrated of Shakespeare's plays offers us a literary mystery which has captured the attention of all who have come into contact with it. It's time to file the question under "Unsolved Mysteries." But for those who persist in analyzing the plot of the drama, or Hamlet's psychology, or both in order to explain this particular enigma, I suggest that you're looking in the wrong place. Try history.    Works Cited    *A. C. Bradley, "Shakespeare's Tragic Period-Hamlet," Shakespearean Tragedy, MacMillan and Company Limited, 1904, pp. 70-101   

Monday, November 11, 2019

Malcolm a Homemade Education Essay

Down syndrome is the most common cause of mental retardationDown syndrome is the most common cause of mental retardation. It is caused by the presence of an extra chromosome. Chromosomes contain sequences of DNA called genes that represent the genetic information that exists within a cell. Twenty-three distinctive pairs of chromosomes which is 46 in total. They are located within the nucleus (a region of the cell that is bounded by a specialized membrane, and which houses the genetic material). When a sperm cell fertilizes an egg cell, the newly created zygote normally receives 23 chromosomes from each parent. The contribution of genetic information from each parent is what makes each baby a distinctive blend of both characteristics. In Down syndrome a mistake during division of the sperm or egg cell produces a cell with an extra chromosome 21. This event occurs during cell division and is referred to as nondisjunction, or the failure of all chromosomes to separately properly resulting in retention of one of the chromosomes in one of the two new daughter cells. This is also called trisomy 21 and is accounted for 95% of all Down syndrome patients. A rare number of Down syndrome cases the original egg and sperm cells begins with the correct number of chromosomes but shortly after fertilization during the phase where cells are dividing rapidly a single cell can divide abnormally creating a line of cells with an extra chromosome 21. It’s called a cell line mosaicism. The individual with this type of down syndrome has two types of cells: some 46 chromosomes which is the normal number and some with 47. Individuals who are mosaic for trisomy 21 typically have less sever sign and symptoms of the disorder. Another are location that can cause down syndrome is called a chromosome translocation. This is an even that unlike the numerical abnormally causing trisomy 21, there is a structural abnormality. Exchange of material from two different chromosomes during the production of sex cells can take place such that there is a whole chromosome 21 attached to another chromosome but the chromosome number is normal. [1]These types of translocation involving chromosome 21, occur in about 3-4% of cases of Down syndrome. Ancient cultures, such as those in Greece, Rome, and Egypt, put disabled infants to death. Compassion toward the disabled was awakened by the early Christian church, but its charitable influence waned during the middle ages. Down syndrome also affected this people due to no one really caring about what was going on with the ill children. Down syndrome has a lot of causes and this is normally what some parents want to know is why their child is born with this syndrome. Most times this is why they tell you while you are carrying your child you need to watch very closely and look for all signs of genetic disorders with pregnant. Down syndrome is a chromosomal disorder as I said before. A baby is usually identified at birth through observation of a set of common physical characteristics. Babies with Down syndrome tend to be overly quiet. When I say that I mean less responsive with weak floppy muscles. With that being said a number of physical signs might be present. This includes a flat bridge of the nose which is smaller than normal. It’s a low set nose. They will tend to have a small mouth with a protruding tongue, upward slanting eyes and also extra folds of skin located at the corner of each eye, near the nose. They will have small outwardly rotated ears and small hands as well. Usually they have an unusual deep crease across the center of the palm and a malformed fifth finger. They will have a wide space between the big and the second toes and unusual creases on the soles of the feet. They also experience shorter than normal height later on in their childhood. Before genetic testing became available, Down syndrome was diagnosed based on certain typical physical characteristics. Not all people with Down syndrome have all these characteristics though. This can vary from certain people and are caused by the extra chromosomes. Individuals with Down syndrome also have joints that are looser than normal. Their skulls are short and broad. Newborns usually have extra skin on the back of their neck, and as the child gets older the neck often appears short and wider than usual. [2]Facial shape is round in the newborn and also during infancy. When the child gets older their face shape becomes oval like. This is due to the underdevelopment they go through. Their cheeks are round and the teeth develop late and in an unusual order. Although Down syndrome is not curable and there will be no cure for it, parents, researchers, and also the Down syndrome individuals try to make the best out of life and try dealing with it. Advances in medical treatment over the past 40 to 50 years for conditions such as heart defects and respiratory disease have led to dramatic increases in the life expectancy of those with Down syndrome. [3] Half of the children born with Down syndrome during the late 1960s survived to age 5. Bronchopneumonia, a respiratory illness and heart defects were the most common causes of death. Now about 80% of those born with it survive to age 10, and about 50% of them survive to age 50 or beyond. The recent statistics from various study places show that the place of incidence of Down syndrome anywhere from 1 in 600 to 1 in 1,000 live births. An analysis published by various people. Bray and colleagues in 1998 of combined data from nine different studies found that the incidence varies from 1 in 1,445 live birth mothers at age 10 to 1 in 25 live births to mothers at age 45. Down syndrome really is a hard disorder to live with but at the same time it has its advantages. Down syndrome has no treatment options but they have a lot of programs to help cope with this syndrome. The development of a child is a joyous thing. It involves amazing ohhs and ahhhs that would shock you every day your child does something new. All kids from the time their able to sit up by them and walks are learning new things everyday. Even as adults we learn new things everyday but still with Down syndrome, everything that they accomplish is outstanding. All kids learn to develop their fine motor skills but there are different aspects when it comes to Down syndrome children. The development of motor skills is very hard. The first thing you have to do is have a laid out foundation of how you plan on teaching that child. This is very dependent on stability. [4]Stability is being able to push open a heavy door. It’s being able to put on your shoes without falling. It is carrying a tray full of drinks. Its really a list that goes on but with this syndrome most things aren’t accomplished because down syndrome babies lack stability. Most of the people diagnosed wit this syndrome also tends to walk a little strange. They walk from side to side and always have their head twisted. Now as kids get older and reach their age past ten, then your not exactly ok, but you can breathe a little. Most researchers are still concerned about the older ones but its really the babies that most are worried about. They tend to go through a lot as newborns and unto there early infants stages. [5] Babies with Down syndrome suffer a lot. They have a lot they feel and go through, but being an infant and not being able to talk doesn’t help at all. Being born with Down syndrome you experience how it is from that point on and for the rest of your life. Children with this syndrome almost always have some degree of intellectual disability. That is why they learn slower and have difficulty with complex reasoning and judgment. The degree of intellectual impairment various tremendously. These kids do learn and what they do learn they will not forget. Down syndrome can not be prevented but it is People with Down syndrome, whatever their age, are people first. They are people with abilities, strengths and weaknesses like everyone else. They may have additional needs but first they have the same needs as everyone else of their age group. The quality of health care, education and community support provided to children and adults with Down syndrome makes a real difference to their progress throughout life. This module provides an introduction to all the issues that need to be addressed to enable individuals with Down syndrome, and their families, to enjoy full and happy lives within their communities. It offers an overview of the development of individuals with Down syndrome from infancy to adult life. It also provides a summary of the causes of Down syndrome, the incidence and prevalence of the condition, life expectancy and associated education and health care needs. Children with down syndrome experience problems with their digestive tract at a rate that is much higher than that of other children. [6] some of these problems such as blockage of the digestice tract can be life threatening and can require emergency surgery. Blockage or atresia of the esophagus or the duodenum can cause starvation if not corrected. Atresia occurs when the anal opening does not develop. This condition prevents solid waste from being eliminated from the intestinal tract and must be corrected surgically. Anal stenosis will allow waste products to pass, but will cause constipation. Gastroesophageal feflux is also more common in individuals with down syndrome. During this stage food reenters the esophagus from the stomach. This can cause vomiting and irritation of the esophagus. You can also have vision problem s with down syndrome to. Theses problems are common with those suffering with down syndrome. Strabismus in which one or both euyes either truns in or out. Occurs in 43% of theses chuldren. It is caused by abnormal or incomplete development of the cneters in the brain that control the coordination of eye movements. This condition may require an eye patch, special glasses or even surgery. Vision therapy may also be benificial and should be considered before surgery. Hearing problems also come with syndrome. [7] anatomical differences that result from trisomy 21 contribute to the larger percentage of hearing difficulties founf in individuals with down syndrome. Appromately 53% in children with down syndrome have hearing problems. This makes it more difficult to examine the ars for wax buildup and infection. The middle ear is smaller than normal, as well. This contributes to the presence of chronic ear infections in 40% to 60% of children with downs syndrome. The shallow nasal bridge founfd in 61% of individuals with down syndrome also contributed. Collapse or blockage of the eustachian tube, which leads from the ear to the throat, causes fluid to build up in the middle ear and increases the risk of middle ear infection. [8]In children with down syndrome the eustachian tubes are often smaller tha normal and have lowered muscle tone. Problems with fluid build up in the middle ear occur in 60% of indiviuals with down syndrome this fluid buildup interferes with hearing and can cause permanent hearing loss if it remains for a long peopif of time. Estimates of hearing loss in people with down syndrome range from 60% to 80%. Hearing loss in children can contribute to language and speech difficulies as well as auditory attention. Monitoring for fluid buildup and infections of the middle ear should begin before the age of six months and should continue into adulthood. Hearin aids may be a choice as well. Another problem that occurs in down syndrome individuals is problems with thyroid gland. Weighing less than one ounce the thyroid is actually one of the largest endocrine glands. Thyroid hormones help regualte the synthesis of growth factore and many hormones. Thyroid hormones are crucial for proper brain development during pregnancy. They are also important in normal growth. Because they are composed of the amino acid tyrosine, to which iodine molecules have been atattched adequate iodine in the diet is esstenial for their production. Another hormone produced by the thyroid gland is calcitonin which regulates the levels and metabolism of calcium. The hormones tri-iodothyonine and tetraiodothyonine are produced by the thyroid gland in a ratio of 1;14. t4 is secreted by the thyroid gland in responses to TSH. The active form, T3 is formed in the kidney, liver, and pleen by removal of one iodine molecule from T4. individuals with down syndrome also are 10 to 30 times more likely to develop Leukemia. [9] This is a type of cancer caused by the production of abnormal qhite blood cells by the bone marrow. These abnormal cells eventually crowd out normal white and red blood cells. There are two main types of leukemia. Acute and chronic. Acute leuk emias develop slowly and the patienst condition worsens slowly. Chronic leukemia develops rapidly and the patients syptoms worsen quickly. About 10% of babies born with down syndrome develop a transient leukemia that usually goes away by 3 months of age. About 20% to 30% of those with this transient condtion go on to develop acute leukemia. Babies who do not have down syndrome rarely have the transient form of leukemia. This higher risk of leukemia is in contrast to the risk of other types of cancer in individuals with down syndrome. The incidence of most types of solid tumors is muh smaller than in the general population. Down syndromes rates has also increased. From 1979 to 2003, the prevalence (total number of cases of a disease in a population at a specific time) of Down syndrome (DS) at birth increased by 31 percent, from 9 to 12 per 10,000 live births in 10 US regions. Within the 10 regions, birth prevalence of DS ranged from a low of 9. 7 in Arkansas to a high of 13. 7 in Utah during 1997-2003. The number of infants born with DS was almost 5 times higher among births to older mothers (38. 6 per 10,000) than among births to younger mothers (7. 8 per 10,000). In 2002, DS was found to be present in about 1 of every 1,000 children and adolescents aged 0 to 19 living in 10 chosen regions of the United States, which means that approximately 83,000 children and adolescents with DS were living in the United States during that year. Prevalence of DS by age group was the highest in 0-3 year olds at 11. , declining to 10. 3 among 4-7 year olds, 9. 8 among 8-11 year olds, 8. 3 among 12-15 year olds, and 6. 0 among 16-19 year olds. A screening test will help identify the possibility of Down syndrome. Screening tests do not provide conclusive answers, but rather, they provide an indication of the likelihood of the baby having Down syndrome. An abnormal test res ult does not mean that your baby has Down syndrome. The goal with a screening test is to estimate the risk of t baby having Down syndrome. If the screening test is positive and a risk for Down syndrome exists, further testing may be recommended. Diagnostic tests can identify Down syndrome before the baby is born. January issue of Obstetrics & Gynecology, the American College of Obstetricians and Gynecologists released guidelines recommending screening for Down syndrome to all pregnant women during their first trimester. Agnostic tests tend to be more expensive and have a degree of risk; screening tests are quick and easy to do. However, screening tests have a greater chance of being wrong; there are â€Å"false-positive† (test indicates the baby has the condition when the baby really does not) and â€Å"false-negatives† (baby has the condition but the test indicates they do not). As far as those individual kids with Down syndrome there is a lot that they can do, just as the regular ones. Kids with Down syndrome tend to have a sense of humor. Those with this disorder have slurred words and stutter but what you can understand they have pretty good conversation. Also in about 4 percent of all down syndrome cases the individual possesses not an entire third copy of chromosome 21 material, which has been incorporated via a translocation into a no homologous chromosome. In translocation pieces are swapped between two non-related chromosomes forming hybrid chromosomes. The most common translocation associated with Down syndrome is that between the long arm (down gene area) of chromosome 21 and an end of chromosome 14. [10] The individual in whom the translocation has occurred shows no evidence of the aberration since the normal complement of genetic material is still present only a different chromosomes location. The difficulty arises when this individual forms gametes. A mother who possesses the 21/14 translocation, for example has one normal 21 one normal 14 and the hybrid chromosomes. She is a genetic carrier for the disorder because she can pass it on to her offspring even though she is clinically normal. The mother can produce three types of viable gametes: one containing the normal 14 and 21. the presence of an extra copy of the long arm of chromosome 21 causes defects in many tissues and organs. One major effect of Down syndrome is mental retardation. The intelligence quotients of affected individuals are typically in the range of 40-50. The IQ varies with age but being higher in childhood than in adolescence or adult life. The disorder is often accompanied by physical traits. Trisomy 21 is one of the most common chromosomal aberrations occurring in about 0. 5 percent of all conceptions and in one out of every seven hundred to eight hundred live births. About 15 percent of the patients institutionalized for mental deficiency suffer from Down syndrome. Before the chromosomal basis for the disorder was determined the frequency of Down syndrome births was correlated with increased maternal age. For mothers at age twenty the incidence of down syndrome is about 0. 5 percent which increases to 0. 9 percent by the age thirty-five and 3 percent at age forty-five. Comparing the chromosomes of the affected offspring with those of both parents have shown that the nondisjunction event is maternal about 75 percent the time. The maternal age effect is thought to result from the different manner in which the male and female gametes are produced. Gamete production in the male event in females. Formation of the femaleâ €™s gametes begins early in embryonic life, somewhere but between the eight and twentieth weeks. During this time, cells in the developing ovary divide rapidly by mitosis forming cells called primary oocytes. These cells then begin meiosis by pairing up the homologues. The process is interrupted now and the cells are held in a state of suspended animation until needed in reproduction, when they are triggered to complete their division. Most individuals with Down syndrome have intellectual disability in the mild (IQ 50–70) to moderate (IQ 35–50) range, with individuals having Mosaic Down syndrome typically 10–30 points higher. Dr. Weihs notes the mental qualities of people with Down syndrome to be â€Å"unisexual,† â€Å"playful,† â€Å"affectionate,† â€Å"mischievous† and â€Å"imitative†. [21]Language skills show a difference between understanding speech and expressing speech, and commonly individuals with Down syndrome have a speech delay. Fine motor skills are delayed and often lag behind gross motor skills and can interfere with cognitive development. Effects of the condition on the development of gross motor skills are quite variable. Some children will begin walking at around 2 years of age, while others will not walk until age 4. Physical therapy, and/or participation in a program of adapted physical education (APE), may promote enhanced development of gross motor skills in Down syndrome children. A 2002 literature review of elective abortion rates found that 91–93% of pregnancies in the United Kingdom and Europe with a diagnosis of Down syndrome were terminated. [54] Data from the National Down Syndrome Cytogenetic Register in the United Kingdom indicates that from 1989 to 2006 the proportion of women choosing to terminate a pregnancy following prenatal diagnosis of Down syndrome has remained constant at around 92%. In the United States a number of studies have examined the abortion rate of fetuses with Down syndrome. Three studies estimated the termination rates at 95%, 98%, and 87% respectively. Medical ethicist Ronald Green argues that parents have an obligation to avoid ‘genetic harm’ to their offspring, and Claire Rayner, then a patron of the Down’s Syndrome Association, defended testing and abortion saying â€Å"The hard facts are that it is costly in terms of human effort, compassion, energy, and finite resources such as money, to care for individuals with handicaps†¦ People who are not yet parents should ask themselves if they have the right to inflict such burdens on others, however willing they are themselves to take their share of the burden in the beginning some physicians and ethicists are concerned about the ethical ramifications of the high abortion rate for this condition. [59] Conservative commentator George Will called it â€Å"eugenics by abortion†. 60] British peer Lord Rix stated that â€Å"alas, the birth of a child with Down’s syndrome is still considered by many to be an utter tragedy† and that the â€Å"ghost of the biologist Sir Francis Galton, who founded the eugenics movement in 1885, still stalks the corridors of many a hospital†. Doctor David Mortimer has argued in Ethics & Medicine that â€Å"Down’s syndrome infants have long been disparaged by some doctors and government bean counters. Some members of the disability rights movement â€Å"believe that public support for prenatal diagnosi s and abortion based on disability contravenes the movement’s basic philosophy and goals. Peter Singer argued that â€Å"neither hemophilia nor Down’s syndrome is so crippling as to make life not worth living from the inner perspective of the person with the condition. To abort a fetus with one of these disabilities, intending to have another child who will not be disabled, is to treat fetuses as interchangeable or replaceable. If the mother has previously decided to have a certain number of children, say two, then what she is doing, in effect, is rejecting one potential child in favor of another. She could, in defence of her actions, say: the loss of life of the aborted fetus is outweighed by the gain of a better life for the normal child who will be conceived only if the disabled one dies. Individuals with Down syndrome have a higher risk for many conditions. The medical consequences of the extra genetic material in Down syndrome are highly variable and may affect the function of any organ system or bodily process. Some problems are present at birth, such as certain heart malformations. Others become apparent over time, such as pilepsy. Other things Down syndrome patients go through are very emotional. For people with Down syndrome it is very hard to cope with the everyday activities. It is also hard on the family, especially the parents. It can be very frustrating for the parents to cope with having a child with Down. People born with Down syndrome require so much more extra attention than that of a normal child. Suggestions from some psychologists are for the parents to go to some kind of group sessions to talk to other parents who have children with Down. Therefore, someone else can understand the frustrations that they go through in raising their child. People with Down syndrome have a lot of different emotions running through their mind and body. People with Down syndrome, whatever their age, are people first. They are people with abilities, strengths and weaknesses like everyone else. They may have additional needs but first they have the same needs as everyone else of their age group. The quality of health care, education and community support provided to children and adults with Down syndrome makes a real difference to their progress throughout life. This module provides an introduction to all the issues that need to be addressed to enable individuals with Down syndrome, and their families, to enjoy full and happy lives within their communities. It offers an overview of the development of individuals with Down syndrome from infancy to adult life. It also provides a summary of the causes of Down syndrome, the incidence and prevalence of the condition, life expectancy and associated education and health care needs. Further modules in this series address each of these issues in detail. Down syndrome patients also have another way to look at things. The most of the time feel different and out of place. Most would like to know who Down syndrome affects. For instance what race and what are the ratios of living past a teenager Children and adults with Down syndrome have a wide range of abilities. A person with Down syndrome may be very healthy or may have unusual and demanding medical and social problems at virtually every stage of life. It’s important to remember that every person with Down syndrome is a unique individual. Each child will develop at his or her own pace. It may take children with Down syndrome longer than other children to reach develop Down syndrome cannot be cured. However, early treatment can help many people with Down syndrome to live productive lives well into adulthood. Children with Down syndrome can often benefit from speech therapy, occupational therapy, and exercises to help improve their motor skills. They might also be helped by special education and attention at school. Some of the medical problems common in people with Down syndrome, like cataracts, hearing problems, thyroid problems, and seizure disorders, can be also treated or corrected. It has been suggested that children with Down syndrome might benefit from medical treatment that includes amino acid supplements and a drug known as Piracetam. Piracetam is a drug that some people believe may improve the ability of the brain to learn and understand. However, there have been no controlled clinical studies with Piracetam to date in the U. S. or elsewhere that show its safety and efficacy. The life expectancy for people with Down syndrome has increased substantially. In 1929, the average life span of a person with Down syndrome was nine years. Today, it is common for a person with Down syndrome to live to age 50 and beyond. In addition to living longer, people with Down syndrome are now living fuller, richer lives than ever before as family members and contributors to their community. Many people with Down syndrome form meaningful relationships and eventually marry. Now that people with Down syndrome are living longer, the needs of adults with Down syndrome are receiving greater attention. With assistance from family and caretakers, many adults with Down syndrome have developed the skills required to hold jobs and to live semi-independently mental milestones, but many of these milestones will eventually be met.

Saturday, November 9, 2019

Differences and Similiraties Between Dickens and Hardy Essay

Dickens was born in Portsea, in 12. His father, John Dickens, was a kind and likeable man, but incompetent with money, and due to his financial difficulties they moved to Camden when Dickens was nine. When Charles was twelve his father was arrested and taken to the debtors’ prison in Southwark. He started working at Warren’s blacking-warehouse and its strenuous working conditions made an impression on him, later influencing his fiction. He became interested in writing (and acting) and, after having learnt shorthand in his spare time, he began working as a freelance reporter at the Parliament and the Old Bailey. Under the nom de plume Boz he published the eponymous Sketches (36), a collection of short pieces concerning London scenes and people. In 36 he married Catherine Hogarth, the daughter of a fellow editor, yet this union proved to be an unhappy one and, though she bore him ten children, he decided to separate from her after 22 years, having fallen in love with an 1 8-year-old actress, Ellen Ternan. This fact often constituted a reason of doubt, regret and depression for his Victorian frame of mind. The Sketches were immediately followed by the Posthumous Papers of the Pickwick Club, a publication in installments which confirmed his success as a humorist and satirist. His rise to fame continued with Oliver Twist (38), David Copperfield (49-50), Little Dorrit (57), all influenced by his childhood memories (he purportedly had a near-photographic memory), and his journalistic career. By means of subtle irony, he denounced the exploitation of children in the slums and factories. His later novels Bleak House (53), Hard times (54) and Great Expectations (60-1) revolve around various social issues, emphasizing the difficult condition of the working class and the poor. Throughout his life he edited several newspapers and magazines, e.g. Household Words or All The Year Round, which hosted serializations of many prominent novels. His last years were marked by numerous reading tours, even in America, and the foundation of charities to help the poor. After his death in 70 his remains were b uried in the Poets’ Corner in Westminster Abbey. Above all, Dickens was a storyteller, as he was influenced by the Bible, fairy tales, fables and nursery rhymes as well as 18th-century essayists and Gothic novelists. His novels have been praised – from Tolstoj to Orwell – for their realism and good story planning. On the other hand, Wilde and Virginia Woolf complained of their episodic nature and artificial vein of saccharine sentimentalism. Of course the publication in monthly or weekly installments imposed strict terms, preventing unified plotting and creating pressure on Dickens to suit the taste of the audience. Most of his novels are set in London, a city he knew well and of which he gave vivid and realistic sketches. In Dickens’s first works, his characters are taken from the bourgeoisie, although often satirized, whereas in the latter novels he presents a more radical point of view on society, still without being a revolutionary thinker. His awareness of the increasing spiritual and material corruption as a consequence of industrialization made him more and more critical of society. His mature works managed to draw popular attention to public abuses, evils and injustices by means of the juxtapositions of terrible descriptions of London desolation and crime and hilarious sketches of the city. He created caricatures by exaggerating and ridiculing the distinctive social characteristics of the middle, lower and lowest classes in their own voices and conversations. His female characters are feeble, and either completely good or irrecoverably evil (a black-and-white morality possibly derived from his difficult relation with his mother). He sympathizes with the poor and the outcast: he shifts the perspective from the upper middle-class world of 18th-century fiction to the life of the lower orders and the working class. Children are often the most relevant characters in his works, a means to fictionally invert the natural or der of things, as their good-natured personality makes them more likely to be the moral teachers than the pupils of the adults (either into insignificant parents or hypocritical grown-ups), the exempla than the imitators. He succeeds not only in making his readers sympathize with the children, but also in proposing them as models of the correct way people should behave to one another. His aim lies in teaching a moral lesson to the reader. To accomplish this he uses the most effective language, i.e. a careful selection of adjectives, lexical and syntactical repetitions, juxtapositions of images and ideas and hyperbolic and ironic comments, thus achieving the most vivid depictions of life and character ever attempted by any novelist. In Coketown, a fictitious industrial town, Thomas Gradgrind, an educator firmly believing in facts and figures, has founded a school based on the suppression of imagination and feelings, the same theories by which he raises his children Louisa and Tom. His daughter is compelled to marry Josiah Bounderby, a wealthy banker thrice her age, and she accepts so that her brother can be apprenticed at Bounderby’s bank, yet the marriage proves to be unhappy. Tom, grown up to be dissipated and self-interested, robs his employer, initially managing to make everyone suspect an honest laborer, Stephen Blackpool , then discovered and snuck out of the country by his sister. Hard Times is composed of three books of three chapters each: Sowing, about the seeds planted by means of the Gradgrind/Bounderby method, Reaping, showing which fruit the plants have borne (Luisa’s unfortunate marriage, Tom’s dishonesty/hedonism which leads to Stephen’s framing) and Garnering, disclosing further details. Hard times revolves around the dichotomy in Dickens’s age between the rich and the poor. The Hands are forced to work interminable shifts for terrible wages in squalid and dangerous factories, with no hope of improving their living or working conditions due to their lack of education and job skills. Through his characters and stories he denounces this gap, thus criticizing the money-oriented and narrow-minded nature of Utilitaria nism, the prevalent approach to economics in Victorian England, which, according to Dickens was transforming humans into machines by forbidding the development of any form of emotion or imagination. In fact, Gradgrind indoctrinates the children of the school, as well as his own, into his system of facts, whereas Bounderby considers his laborers nothing more than emotionless objects to be exploited at his own liking. Mr. Gradgrind argues that nature is a measurable, quantifiable entity entirely dominated by rational principles, and strives to transform the pupils of his school into little machines unquestioningly following these rules. Dickens’s objective lies in showing how dangerous allowing the â€Å"mechanization† of humans can be, hinting that with no compassion and imagination life would be unendurable. The extract is centered on the description of the Victorian industrial Coketown, a fictitious Northern-English mill-town whose name, the town of coke (coke being a fuel derived from the distillation of coal) is meaningful as it hints at the contribution of industrial pollution to the blackening of buildings. This town is an unpleasant place, where everything is a triumph of fact (all fact, workful): it is not only polluted, as demonstrated by â€Å"the unnatural red and black† and the â€Å"river than ran purple with ill-smelling dye†, but also noisy, due to the never-ending â€Å"rattling and trembling† of the steam-engine (one of the symbols of industrialization). Dickens employs metaphors and similes connected with nature, yet they all have negative and unsettling undertones, as the savage is war-donned, the serpents never-uncoiling, the elephant in â€Å"melancholy madness† (i.e. in musth). Therefore life in Coketown is not only marked by unpleasant alienation as well as by a fundamental opposition to the laws of nature and common sense. The whole place is monotonous as not only the streets are very similar to one another, but also the people, synchronized in all their activities. Even public buildings are standardized, looking like factories with â€Å"no taint of fancy† as artistic expression is contrary to Utilitarianism. Dickens was an important denouncer of the vices and injustices of Victorian England, employing fiction as a means to condemn public evils and abuses. He drew popular attention to the cruelty of some schools, to the squalid misery of London slums and its criminal underworld by means of his social/humanitaria n novels. He greatly influenced the contemporary reform movement, yet he was not a revolutionary per se, as he never questioned the pre-constituted order of his time, as noted by Orwell. He advocated a change not in the whole society but in the single individual, who is the real target of his moral, not political or revolutionary, message. He argued that if men behaved decently, the world would be decent, and made good win over evil in his novels as a sign of his fundamental optimism. Hardy was born of a humble family in Upper Bockhampton , a hamlet in Dorset, in 40. He became apprenticed to a local architect at sixteen and then moved to London. He read a lot, including the works of Comte, Mill, Darwin and Schopenhauer, who all influenced his novels, especially Schopenhauer, from whose The World as Will and Idea he adopted the notion of Immanent Will. His first success was Far from the Madding Crowd, published in installments throughout 74. His fame increased even further with a series of tragic novels: the Mayor of Casterbridge (86), the Woodlanders (87), Tess of the d’Urbervilles (91) and Jude the Obscure (95). The last book caused an outrage due to its nihi lism and immorality: dubbed Jude the Obscene by some, it was publicly burnt by the bishop of Wakefield. Its negative reception induced Hardy to turn his efforts exclusively to poetry. After his death in 28 his ashes were buried in the Poets’ Corner in Westminster Abbey. Hardy’s characters are defined through their surroundings. His works are set in Wessex, a semi-fictional county in South West England corresponding to Dorset based on the eponymous Saxon medieval reign (as stated in the Preface to Far from the Madding Crowd). Being an architect, he had an exceptional sense of place, which allowed him to describe medieval ruins as well as important landmarks like Stonehenge or the college of Oxford. His early life in Dorset granted him with an extensive knowledge of the folk traditions connected with country gatherings or fairs. In his novels the rural group assumes a role similar to that of ancient Greek choruses, commenting on the actions of the character, either to provide the reader with an interpretation or a form of light relief. In the village of Marlott, the poor pe ddler John Durbeyfield is stunned to discover that he is descended from the D’Urbevilles, a once-wealthy aristocratic Norman family now extinct. The difficult conditions of his family worsen after the death of their horse caused by their eldest daughter Tess, who consequently agrees to go to the D’Urberville estate and â€Å"claim kin† (unaware of its non-existence). She gets a position as a poultry maid thanks to Alec, the mistress’s lascivious son who constantly makes undesired advances on her. He eventually takes advantage of her after a fair. She returns home and gives birth to a sickly child, who is christened Sorrow just before his death. After a year she seeks employment far from her past, i.e. in a distant valley, becoming a milkmaid at the Thalbothays Dairy. There she re-encounters Angel, a reverend’s son apprenticing as a farmer. They fall in love, yet Tess is uncertain whether to reveal him her past and resolves to slip a confessional letter under his door, which unfortunately ends under the carpet. The marriage goes smoothly nevertheless when on their wedding night they confess each oth er their past Angel is struck dumb, and resolves to leave her, boarding a ship for Brazil. Tess experiences many sufferings and difficulties and is obliged to accept a job at an hardscrabble farm. During a walk she overhears a wandering preacher who turns out to be none else than Alec, converted to Methodism by Reverend Clare. Tess eventually accepts his proposal to support her family after her father’s death. However, Angel returns from Brazil and seeks Tess to ask her forgiveness, but she stoically refuses. Heartbroken to the point of madness, she stabs Alec to death and flees to Angel. She is arrested at Stonehenge, where she felt asleep on a large rock, and is eventually executed. He is the most important pessimistic novelist of late Victorian England due to many reasons: first of all, he was born in the Hungry 40s, a period in which the price of bread was kept high by the Corn laws and many people starved to death; secondly his first marriage was an unhappy, childless one, though he felt remorseful after his wife’s death; lastly he was influenced by Darw in and his vision of life as a never-ending struggle for the survival of the fittest as well as by Schopenhauer ‘s universe governed by the blind â€Å"Immanent will†, and he started to put into discussion his religious faith. Furthermore, he was profoundly touched by the collapse of the rustic world, which he loved and experienced first-handedly since his birth. In fact his county, Dorsetshire, in South West England, was suffering from the consequences of the mechanization of agriculture, the severe economic crises of the 70s and the mass-migration to the towns. Hardy argues that life is a struggle for survival against wicked impersonal powers. Love is a destructive natural instinct. In fact man is in thrall to fate, i.e. an impersonal unforeseeable entity governing over both the inside and outside of man (personality and surroundings). Therefore human life is nothing but a useless, excruciating struggle with destiny, also known as Immanent will as per his reading of Arthur Schopenhauer . It is a kind of Anti-Providence, an unstoppable apparatus operating through a series of unfortunate coincidences. According to Hardy, the universe is at the mercy of Chance, blindfolded casualness either unconcerned or antagonistic to man. As a matter of fact, in Tess this malignant power amuses itself by tormenting her to death. â€Å"Justice was done, and the President of the Immortals, in Aeschylean phrase, had ended his sport with Tess†. Tess, and, more generally, man, is a marionette in the hands of Chance, a worthless varmint in the universe. Tess is fated to sorrow and death from the very moment she came into being. There are three important themes in his works: the difficulty of being alive; nature, unaffected by man’s fate yet co-protagonist with him; Victorian hypocrisy, which is criticized as well as conventional moralism, in particular as far as women are concerned: in fact Tess, a falling woman as per Victorian morals, is presented as a pure, guiltless vict im of chance and her love interests. His language is measured, abundant in details and symbolism. The metaphors, similes and personifications he employs reflect his love for nature. The language of sense impressions is central to his writing, as objects are perceived through touch, sight, sound and smell. Though his novels were composed during a period of literary experimentation, he persevered in employing the Victorian omniscient narrator, who is always present, sometimes commenting on the characters or events by expressing his opinions and view on life. Furthermore, he anticipates the cinema in that he employs narrative techniques alike to the camera eye and the zoom (e.g. in Far from the madding crowd).

Thursday, November 7, 2019

Synthesis Reaction Definition and Examples

Synthesis Reaction Definition and Examples A synthesis reaction or direct combination reaction is one of the most common types of chemical reactions. In a synthesis reaction, two or more chemical species combine to form a more complex product. A B → AB In this form, a synthesis reaction is easy to recognize because you have more reactants than products. Two or more reactants combine to make one larger compound. One way to think of synthesis reactions is that they are the reverse of a decomposition reaction. Synthesis Reaction Examples In the simplest synthesis reactions, two elements combine to form a binary compound (a compound made of two elements). The combination of iron and sulfur to form iron (II) sulfide is an example of a synthesis reaction: 8 Fe S8 → 8 FeS Another example of a synthesis reaction is the formation of potassium chloride from potassium and chlorine gas: 2K(s) Cl2(g) → 2KCl(s) As in these reactions, its common for a metal to react with a nonmetal. One typical nonmetal is oxygen, as in the everyday synthesis reaction of rust formation: 4 Fe (s) 3 O2 (g) → 2 Fe2O3 (s) Direct combination reactions arent always just simple elements reacting to form compounds. Another everyday example of a synthesis reaction is the reaction that forms hydrogen sulfate, a component of acid rain. Here, the sulfur oxide compound reacts with water to form a single product: SO3 (g) H2O (l) → H2SO4 (aq) So far, the reactions you have seen have only one product molecule on the right-hand side of the chemical equation. Be on the lookout for synthesis reactions with multiple products. A familiar example of a more complex synthesis reaction is the overall equation for photosynthesis: CO2 H2O → C6H12O6 O2 The glucose molecule is more complex than either carbon dioxide or water. Remember, the key to identifying a synthesis or direct combination reaction is to recognize two or more reactants form a more complex product molecule! Predicting Products Certain synthesis reactions form predictable products: Combining two pure elements will form a binary compound.The product formed by reacting a metallic oxide and carbon dioxide will be a carbonate.Binary salts react with oxygen to form a chlorate.

Monday, November 4, 2019

Intro to business Research Paper Example | Topics and Well Written Essays - 500 words

Intro to business - Research Paper Example spending i.e., food and beverages, and recorded a steady growth; in a way it invented a new market structure through its monopolistic structure, a thorough competitive activity, industry costs and capital structure, all achieved through a systematic approach and healthy business practices. Its journey from Seattle to other parts of the United States and then rest of the world is said to have begun in the 1990s (Starbucks Coffee Company, par.1). Although Starbucks’ main products include a variety of coffee, they also provide food services within the same outlets. Their main business objectives include production of high quality product, aim for customer delight, ensuring utmost employee satisfaction and strategic business performance. Operating in multiple locations across the globe requires a great deal of effort, excellent team of executives and an effective leadership. Starbucks’ leaders infused this culture into every employee through healthy management practices such as team working, training, empowerment of employees, alignment to the mission and vision of Starbucks, appropriate performance measurement and feedback system. From a business perspective, their supply chain network is highly established and well managed through practices such as Coffee and Farmer Equity (C.A.F.E ) program, supplier certification, and robust product evaluation mechanisms. It also abides by all the social, legal, ethical responsibilities towards environment and State through appropriate practices (Starbucks Corporation, p.22). Starbucks has laid much stress on continuous improvement, which includes a continuous identification of areas of improvement; taking up these areas as opportunities to perform better and has successfully implemented Total Quality Management (TQM) system in all sectors (Starbucks Corporation, p.11). The advantages of such business include potential to attract more customers, continuous revenue generation, increasing popularity and can attract best

Saturday, November 2, 2019

Quality and Environmental Management Report Essay

Quality and Environmental Management Report - Essay Example The philosophy regards the processes to be problematic in general and not the employees. Customer satisfaction being the top aim in a quality management system, good leadership and power delegation at different employee levels for increased participation and teamwork. To achieve total quality management, processes and tools must be integrated with each other and the system itself to be recursively controlled by quality assurance check. Inspite of developing quality control methodologies, many European and American companies have not been able to attain much benefit from them. This is mostly because of lack of insight in implementation and mismatches between processes and problems. This means quality management should be treated as a due process with careful choosing of tools. There is a number of quality assurance tools that can be deployed to support a good quality management system for the house manufacturing company. Since the company is producing prefinished products to support t he on site construction, it is essential that the prefinished components are of good quality as evident by the problem occurring for the company. The basic tools to be deployed for the prefinished products range from production floor to advanced technologies and methods including ISO 9001, total quality management and Six sigma method. Seeing that the company already has a production floor as shown in the brief, it can be improved by adapting to Lean manufacturing in addition to these can help the company reduce the costs as well as increase the quality of their products by eliminating any processes and methods that are not useful for the finished product and customer demand. This will be a sure way to save space in the allocated workshops, clean up the processes and have only the customer oriented processes running. With the continuous improvement from total quality management and statistical controls of the Six sigma method, the defects in the prefabrications should be eliminated. As far as the actual causes of the defects occurring in the products are well handled and eliminated, the finished houses will be of good quality. 2. Plan and describe an appropriate ISO 9001 compliant Quality Management System (QMS), which the organization could employ to improve their quality problems. By meeting unique customer requirements and avoiding non-conformities ISO 9001 can help the company achieve full customer satisfaction (Cianfrani & West 2009). To comply with the industrial standards ISO quality standard improves internal operations and also covers the design research and development. Since the company’s construction is tied to the production of the prefinished products, a holistic approach is the best way to proceed. An appropriate quality management system to comply with a comprehensive set of standards to ensure quality for the customers would be to set up an appropriate organization structure for the company (Case Management Advisor 2004). An appropriate organization structure is a basic set of compliant quality management system that ISO 9001 gives. The organization should start from the top of the organization structure to improve the processes by fixing the processes management structure. The top management should be given clear policies to fully communicate the required products and customer requirem